The RDE-10/RDE-11 complex triggers RNAi-induced mRNA degradation by association with target mRNA in C. elegans

The molecular mechanisms for target mRNA degradation in Caenorhabditis elegans undergoing RNAi are not fully understood. Using a combination of genetic, proteomic, and biochemical approaches, we report a divergent RDE-10/RDE-11 complex that is required for RNAi in C. elegans. Genetic analysis indica...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Yang, Huan, Zhang, Ying, Vallandingham, Jim, Li, Hau, Florens, Laurence, Mak, Ho Yi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2012
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337458/
https://ncbi.nlm.nih.gov/pubmed/22508728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.180679.111
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