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The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling

How self-renewal versus differentiation of neural progenitor cells is temporally controlled during early development remains ill-defined. We show that mouse Lin41 (mLin41) is highly expressed in neural progenitor cells and its expression declines during neural differentiation. Loss of mLin41 functio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Jianfu, Lai, Fan, Niswander, Lee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337455/
https://ncbi.nlm.nih.gov/pubmed/22508726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.187641.112
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