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The Hectd1 Ubiquitin Ligase is Required for Development of the Head Mesenchyme and Neural Tube Closure
Closure of the cranial neural tube depends on normal development of the head mesenchyme. Homozygous-mutant embryos for the ENU-induced open mind (opm) mutation exhibit exencephaly associated with defects in head mesenchyme development and dorsal-lateral hinge point formation. The head mesenchyme in...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2007
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730518/ https://ncbi.nlm.nih.gov/pubmed/17442300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.03.018 |
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