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The Hectd1 Ubiquitin Ligase is Required for Development of the Head Mesenchyme and Neural Tube Closure

Closure of the cranial neural tube depends on normal development of the head mesenchyme. Homozygous-mutant embryos for the ENU-induced open mind (opm) mutation exhibit exencephaly associated with defects in head mesenchyme development and dorsal-lateral hinge point formation. The head mesenchyme in...

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Auteurs principaux: Zohn, Irene E., Anderson, Kathryn V., Niswander, Lee
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730518/
https://ncbi.nlm.nih.gov/pubmed/17442300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.03.018
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