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Antiproliferative effects of antisense oligonucleotides directed to the RNA of c-myc oncogene.

Several groups have reported the use of antisense oligonucleotides to inhibit c-myc gene expression and study its biological role. However high concentrations of free oligonucleotides were generally needed. To lower their concentration and stabilize the antisense effect against c-myc, oligonucleotid...

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Autors principals: Degols, G, Leonetti, J P, Mechti, N, Lebleu, B
Format: Artigo
Idioma:Inglês
Publicat: 1991
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC333736/
https://ncbi.nlm.nih.gov/pubmed/1708128
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