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Screening for Therapeutic Targets of Vorinostat by SILAC-based Proteomic Analysis in Human Breast Cancer Cells

Histone deacetylases (HDACs) play critical roles in silencing tumor suppressor genes. HDAC inhibitors reactivate tumor suppressor genes and inhibit tumor cell growth in vitro and in vivo, and several HDAC inhibitors are currently being evaluated in clinical trials for cancer therapy. A comprehensive...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Zhou, Qun, Chaerkady, Raghothama, Shaw, Patrick G., Kensler, Thomas W., Pandey, Akhilesh, Davidson, Nancy E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337220/
https://ncbi.nlm.nih.gov/pubmed/20049865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200900602
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