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Revertant mosaicism in a human skin fragility disorder results from slipped mispairing and mitotic recombination
Spontaneous gene repair, also called revertant mosaicism, has been documented in several genetic disorders involving organs that undergo self-regeneration, including the skin. Genetic reversion may occur through different mechanisms, and in a single individual, the mutation can be repaired in variou...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336993/ https://ncbi.nlm.nih.gov/pubmed/22466645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61976 |
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