Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice

The acute phase response is an evolutionarily conserved reaction in which physiological stress triggers the liver to remodel the blood proteome. Although thought to be involved in immune defense, the net biological effect of the acute phase response remains unknown. As the acute phase response is st...

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Detaylı Bibliyografya
Asıl Yazarlar: Quinton, Lee J., Blahna, Matthew T., Jones, Matthew R., Allen, Eri, Ferrari, Joseph D., Hilliard, Kristie L., Zhang, Xiaoling, Sabharwal, Vishakha, Algül, Hana, Akira, Shizuo, Schmid, Roland M., Pelton, Stephen I., Spira, Avrum, Mizgerd, Joseph P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2012
Konular:
Brief Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336975/
https://ncbi.nlm.nih.gov/pubmed/22466650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59408
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