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Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity
T-cell development comprises a stepwise process of commitment from a multipotent precursor. To define molecular mechanisms controlling this progression, we probed five stages spanning the commitment process using RNA-seq and ChIP-seq to track genome-wide shifts in transcription, cohorts of active tr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336965/ https://ncbi.nlm.nih.gov/pubmed/22500808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.056 |
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