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The constitutional t(11;22): implications for a novel mechanism responsible for gross chromosomal rearrangements
The constitutional t(11;22)(q23;q11) is the most common recurrent non-Robertsonian translocation in humans. The breakpoint sequences of both chromosomes are characterized by several hundred base pairs of palindromic AT-rich repeats (PATRRs). Similar PATRRs have also been identified at the breakpoint...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336963/ https://ncbi.nlm.nih.gov/pubmed/20507342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-0004.2010.01445.x |
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