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Role of FGF23 in Vitamin D and Phosphate Metabolism: Implications in Chronic Kidney Disease
FGF23 is a bone-derived hormone that regulates systemic phosphate homeostasis, vitamin D metabolism and α-klotho expression through a novel bone-kidney axis. FGF23 inhibits renal tubular reabsorption of phosphate through mechanisms independent of PTH as well as reduces circulating 1, 25(OH)(2)D thro...
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| 第一著者: | |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336874/ https://ncbi.nlm.nih.gov/pubmed/22421513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2012.02.027 |
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