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Phosphorothioate-containing RNAs show mRNA activity in the prokaryotic translation systems in vitro.

Phosphorothioate-containing RNAs were generated by transcription of coliphage T7 DNA using the Sp diastereomers of ribonucleoside 5'-O-(1-thiotriphosphates) and T7 RNA polymerase. RNAs in which a single nucleotide was substituted by the corresponding nucleoside phosphorothioate functioned as mR...

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Hlavní autoři: Ueda, T, Tohda, H, Chikazumi, N, Eckstein, F, Watanabe, K
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC333646/
https://ncbi.nlm.nih.gov/pubmed/2011526
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