Phosphorothioate-containing RNAs show mRNA activity in the prokaryotic translation systems in vitro.

Phosphorothioate-containing RNAs were generated by transcription of coliphage T7 DNA using the Sp diastereomers of ribonucleoside 5'-O-(1-thiotriphosphates) and T7 RNA polymerase. RNAs in which a single nucleotide was substituted by the corresponding nucleoside phosphorothioate functioned as mR...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Ueda, T, Tohda, H, Chikazumi, N, Eckstein, F, Watanabe, K
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1991
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333646/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2011526/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.3.547
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