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Structure–function relationship of the Polo-like kinase in Trypanosoma brucei
Polo-like kinases (Plks) play multiple roles in mitosis and cytokinesis in eukaryotes and are characterized by the C-terminal Polo-box domain (PBD), which is implicated in binding to Plk substrates, targeting Plk and regulating Plk activity. The Plk homolog in Trypanosoma brucei (TbPLK) possesses a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336379/ https://ncbi.nlm.nih.gov/pubmed/22275435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.094243 |
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