The generation and evaluation of two panels of epitope-matched mouse IgG1, IgG2a, IgG2b and IgG3 antibodies specific for Plasmodium falciparum and Plasmodium yoelii merozoite surface protein 1–19 (MSP1(19))

Murine immunoglobulin G (IgG) plays an important role in mediating protective immune responses to malaria. We still know relatively little about which IgG subclasses protect against this disease in mouse models, although IgG2a and IgG2b are considered to be the most potent and dominate in successful...

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Main Authors: Adame-Gallegos, Jaime R., Shi, Jianguo, McIntosh, Richard S., Pleass, Richard J.
格式: Artigo
語言:Inglês
出版: Academic Press 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336205/
https://ncbi.nlm.nih.gov/pubmed/22343045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2012.02.003
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