Inhibition of Erythrocyte Invasion and Plasmodium falciparum Merozoite Surface Protein 1 Processing by Human Immunoglobulin G1 (IgG1) and IgG3 Antibodies

Antigen-specific antibodies (Abs) to the 19-kDa carboxy-terminal region of Plasmodium falciparum merozoite surface protein 1 (MSP1(19)) play an important role in protective immunity to malaria. Mouse monoclonal Abs (MAbs) 12.10 and 12.8 recognizing MSP1(19) can inhibit red cell invasion by interferi...

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Detalhes bibliográficos
Main Authors: Lazarou, Maria, Patiño, José A. Guevara, Jennings, Richard M., McIntosh, Richard S., Shi, Jianguo, Howell, Steven, Cullen, Eilish, Jones, Tarran, Adame-Gallegos, Jaime R., Chappel, Jonathan A., McBride, Jana S., Blackman, Michael J., Holder, Anthony A., Pleass, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786472/
https://ncbi.nlm.nih.gov/pubmed/19805526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00167-09
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