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Alpha-synuclein's degradation in vivo: Opening a new (cranial) window on the roles of degradation pathways in Parkinson disease

Progressive accumulation of α-synuclein is key to the pathology of many neurodegenerative diseases, including Parkinson disease and dementia with Lewy bodies. Increased intracellular levels of α-synuclein may be caused by enhanced expression or alterations in protein degradation pathways. Here we re...

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Bibliografische gegevens
Hoofdauteurs: Ebrahimi-Fakhari, Darius, McLean, Pamela J, Unni, Vivek K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336083/
https://ncbi.nlm.nih.gov/pubmed/22301995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.8.2.18938
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