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The amplified cancer gene LAPTM4B promotes tumor growth and tolerance to stress through the induction of autophagy

Autophagy is a fundamental salvage pathway that encapsulates damaged cellular components and delivers them to the lysosome for degradation and recycling. This pathway usually conducts a protective cellular response to nutrient deprivation and various stresses. Tumor cells live with metabolic stress...

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Autors principals: Li, Yang, Iglehart, J. Dirk, Richardson, Andrea L, Wang, Zhigang Charles
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336080/
https://ncbi.nlm.nih.gov/pubmed/22301992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.8.2.18941
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