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The amplified cancer gene LAPTM4B promotes tumor growth and tolerance to stress through the induction of autophagy
Autophagy is a fundamental salvage pathway that encapsulates damaged cellular components and delivers them to the lysosome for degradation and recycling. This pathway usually conducts a protective cellular response to nutrient deprivation and various stresses. Tumor cells live with metabolic stress...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336080/ https://ncbi.nlm.nih.gov/pubmed/22301992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.8.2.18941 |
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