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Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy
Chloroquine (CQ) is a 4-aminoquinoline drug used for the treatment of diverse diseases. It inhibits lysosomal acidification and therefore prevents autophagy by blocking autophagosome fusion and degradation. In cancer treatment, CQ is often used in combination with chemotherapeutic drugs and radiatio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336076/ https://ncbi.nlm.nih.gov/pubmed/22252008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.8.2.18554 |
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