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Cell permeabilization and inhibition of voltage-gated Ca(2+) and Na(+) channel currents by nanosecond pulsed electric fields

Previous studies have found that nanosecond pulsed electric field (nsPEF) exposure causes long-term permeabilization of the cell plasma membrane. In this study, we utilized the whole-cell patch-clamp method to study the nsPEF effect on currents of voltage-gated (VG) Ca(2+) and Na(+) channels (I(Ca)...

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Bibliografiske detaljer
Main Authors: Nesin, Vasyl, Bowman, Angela M., Xiao, Shu, Pakhomov, Andrei G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336014/
https://ncbi.nlm.nih.gov/pubmed/22213081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bem.21696
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