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Inhibition of voltage-gated Na(+) current by nanosecond pulsed electric field (nsPEF) is not mediated by Na(+) influx or Ca(2+) signaling

In earlier studies, we found that permeabilization of mammalian cells with nsPEF was accompanied by prolonged inhibition of voltage-gated (VG) currents through the plasma membrane. This study explored if the inhibition of VG Na(+) current (I(Na)) resulted from (i) reduction of the transmembrane Na(+...

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Detalhes bibliográficos
Main Authors: Nesin, Vasyl, Pakhomov, Andrei G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330144/
https://ncbi.nlm.nih.gov/pubmed/22234846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bem.21703
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