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Increased DNA methyltransferase activity and DNA methylation following epidermal growth factor stimulation in ovarian cancer cells
Ovarian cancer progression is correlated with accumulation of aberrant CpG island methylation. In ovarian cancer, ascites fluid contains numerous Epidermal-Growth-Factor-Receptor (EGFR) activators, which could result in a tumor microenvironment of constant EGFR activation. Signaling pathways downstr...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335945/ https://ncbi.nlm.nih.gov/pubmed/22430797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.7.3.19273 |
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