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Increased DNA methyltransferase activity and DNA methylation following epidermal growth factor stimulation in ovarian cancer cells
Ovarian cancer progression is correlated with accumulation of aberrant CpG island methylation. In ovarian cancer, ascites fluid contains numerous Epidermal-Growth-Factor-Receptor (EGFR) activators, which could result in a tumor microenvironment of constant EGFR activation. Signaling pathways downstr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335945/ https://ncbi.nlm.nih.gov/pubmed/22430797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.7.3.19273 |
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