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A single nucleotide polymorphism in an exon dictates allele dependent differential splicing of episialin mRNA.
The episialin gene (MUC1) encodes an epithelial mucin containing a variable number of repeats with a length of twenty amino acids, resulting in many different alleles that can be subdivided into two size classes. The episialin pre-mRNA uses either one of two neighbouring splice acceptor sites for ex...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1991
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC333593/ https://ncbi.nlm.nih.gov/pubmed/2014168 |
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