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Rapid turnover of DNA methylation in human cells

Recent studies demonstrated that cytosine methylation in the genome can be reversed without DNA replication by enzymatic mechanisms based on base excision-repair pathways. Both enzymatic methylation and demethylation mechanisms are active in the cell nucleus at the same time. One can hypothesize tha...

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Autori principali: Yamagata, Yoshiaki, Szabó, Pàl, Szüts, David, Bacquet, Caroline, Arányi, Tamàs, Páldi, Andras
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335907/
https://ncbi.nlm.nih.gov/pubmed/22395463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.7.2.18906
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