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Novel Small-Molecule Inhibitors of Hepatitis C Virus Entry Block Viral Spread and Promote Viral Clearance in Cell Culture

Combinations of direct-acting anti-virals offer the potential to improve the efficacy, tolerability and duration of the current treatment regimen for hepatitis C virus (HCV) infection. Viral entry represents a distinct therapeutic target that has been validated clinically for a number of pathogenic...

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Detalhes bibliográficos
Main Authors: Coburn, Glen A., Fisch, Danielle N., Moorji, Sameer M., de Muys, Jean-Marc, Murga, Jose D., Paul, Dorothy, Provoncha, Kathleen P., Rotshteyn, Yakov, Han, Amy Q., Qian, Dapeng, Maddon, Paul J., Olson, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335862/
https://ncbi.nlm.nih.gov/pubmed/22545104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035351
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