Promoters with the octamer DNA motif (ATGCAAAT) can be ubiquitous or cell type-specific depending on binding affinity of the octamer site and Oct-factor concentration.

Immunoglobulin (Ig) gene promoters contain the octamer sequence motif ATGCAAAT which is recognized by cellular transcription factors (Oct factors). Besides the ubiquitous Oct-1 factor, there is also a group of related factors (Oct-2 factors) encoded by a separate gene. The Oct-2 gene is regulated in...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Kemler, I, Bucher, E, Seipel, K, Müller-Immerglück, M M, Schaffner, W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1991
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333585/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2014164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.2.237
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