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Promoters with the octamer DNA motif (ATGCAAAT) can be ubiquitous or cell type-specific depending on binding affinity of the octamer site and Oct-factor concentration.

Immunoglobulin (Ig) gene promoters contain the octamer sequence motif ATGCAAAT which is recognized by cellular transcription factors (Oct factors). Besides the ubiquitous Oct-1 factor, there is also a group of related factors (Oct-2 factors) encoded by a separate gene. The Oct-2 gene is regulated in...

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Bibliografiska uppgifter
Huvudupphovsmän: Kemler, I, Bucher, E, Seipel, K, Müller-Immerglück, M M, Schaffner, W
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC333585/
https://ncbi.nlm.nih.gov/pubmed/2014164
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