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The EYA Tyrosine Phosphatase Activity Is Pro-Angiogenic and Is Inhibited by Benzbromarone

Eyes Absents (EYA) are multifunctional proteins best known for their role in organogenesis. There is accumulating evidence that overexpression of EYAs in breast and ovarian cancers, and in malignant peripheral nerve sheath tumors, correlates with tumor growth and increased metastasis. The EYA protei...

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Main Authors: Tadjuidje, Emmanuel, Wang, Tim Sen, Pandey, Ram Naresh, Sumanas, Saulius, Lang, Richard A., Hegde, Rashmi S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335822/
https://ncbi.nlm.nih.gov/pubmed/22545090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034806
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