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Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling

Germline mutations in the RAS–mitogen-activated protein kinase (RAS/MAPK) pathway are associated with genodermatoses, characterized by cutaneous, cardiac, and craniofacial defects, and cancer predisposition. Whereas activating mutations in HRAS are associated with the vast majority of patients with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mukhopadhyay, Anandaroop, Krishnaswami, Suguna R., Yu, Benjamin D.-Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335744/
https://ncbi.nlm.nih.gov/pubmed/20944652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.296
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