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Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development

Activating mutations in the KRAS oncogene are associated with three related human syndromes, which vary in hair and skin phenotypes depending on the involved allele. How variations in RAS signals are interpreted during hair and skin development is unknown. In this study, we investigated the developm...

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Detalhes bibliográficos
Main Authors: Mukhopadhyay, Anandaroop, Krishnaswami, Suguna Rani, Cowing-Zitron, Christopher, Hung, Nai-Jung, Reilly-Rhoten, Heather, Burns, Julianne, Yu, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536821/
https://ncbi.nlm.nih.gov/pubmed/23123965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.10.024
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