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Evidence for both innate and acquired mechanisms of protection from Plasmodium falciparum in children with sickle cell trait

Sickle cell trait (HbAS) is known to be protective against Plasmodium falciparum malaria, but it is unclear when during the course of infection this protection occurs and whether protection is innate or acquired. To address these questions, a cohort of 601 children 1-10 years of age were enrolled in...

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Detalhes bibliográficos
Main Authors: Gong, Lauren, Maiteki-Sebuguzi, Catherine, Rosenthal, Philip J., Hubbard, Alan E., Drakeley, Chris J., Dorsey, Grant, Greenhouse, Bryan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335384/
https://ncbi.nlm.nih.gov/pubmed/22327223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-371062
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