OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors

Mental retardation and early Alzheimer's disease (AD) have generally been attributed to progressive neuronal loss in the developing and mature Down syndrome (DS) brain. However, reduced neuronal production during development could also contribute to the smaller brain size and simplified gyral p...

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Bibliographische Detailangaben
Hauptverfasser: Lu, Jie, Lian, Gewei, Zhou, Hui, Esposito, Giuseppe, Steardo, Luca, Delli-Bovi, Laurent C., Hecht, Jonathan L., Lu, Q. Richard, Sheen, Volney
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335315/
https://ncbi.nlm.nih.gov/pubmed/22343408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds052
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