OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors

Mental retardation and early Alzheimer's disease (AD) have generally been attributed to progressive neuronal loss in the developing and mature Down syndrome (DS) brain. However, reduced neuronal production during development could also contribute to the smaller brain size and simplified gyral p...

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Hlavní autoři: Lu, Jie, Lian, Gewei, Zhou, Hui, Esposito, Giuseppe, Steardo, Luca, Delli-Bovi, Laurent C., Hecht, Jonathan L., Lu, Q. Richard, Sheen, Volney
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335315/
https://ncbi.nlm.nih.gov/pubmed/22343408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds052
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