Structural changes caused by radiation-induced reduction and radiolysis: the effect of X-ray absorbed dose in a fungal multicopper oxidase

X-ray radiation induces two main effects at metal centres contained in protein crystals: radiation-induced reduction and radiolysis and a resulting decrease in metal occupancy. In blue multicopper oxidases (BMCOs), the geometry of the active centres and the metal-to-ligand distances change depending...

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Bibliographic Details
Main Authors: De la Mora, Eugenio, Lovett, Janet E., Blanford, Christopher F., Garman, Elspeth F., Valderrama, Brenda, Rudino-Pinera, Enrique
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2012
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335286/
https://ncbi.nlm.nih.gov/pubmed/22525754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444912005343
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