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X-ray-induced catalytic active-site reduction of a multicopper oxidase: structural insights into the proton-relay mechanism and O(2)-reduction states

During X-ray data collection from a multicopper oxidase (MCO) crystal, electrons and protons are mainly released into the system by the radiolysis of water molecules, leading to the X-ray-induced reduction of O(2) to 2H(2)O at the trinuclear copper cluster (TNC) of the enzyme. In this work, 12 cryst...

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Библиографические подробности
Опубликовано в: :Acta Crystallogr D Biol Crystallogr
Главные авторы: Serrano-Posada, Hugo, Centeno-Leija, Sara, Rojas-Trejo, Sonia Patricia, Rodríguez-Almazán, Claudia, Stojanoff, Vivian, Rudiño-Piñera, Enrique
Формат: Artigo
Язык:Inglês
Опубликовано: International Union of Crystallography 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934174/
https://ncbi.nlm.nih.gov/pubmed/26627648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715018714
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