Paraoxonases-2 and -3 Are Important Defense Enzymes against Pseudomonas aeruginosa Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties

The pathogen Pseudomonas aeruginosa causes serious damage in immunocompromised patients by secretion of various virulence factors, among them the quorum sensing N-(3-oxododecanoyl)-L-homoserine lactone (3OC12) and the redox-active pyocyanin (PCN). Paraoxonase-2 (PON2) may protect against P. aerugino...

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Autores principales: Schweikert, Eva-Maria, Amort, Julianna, Wilgenbus, Petra, Förstermann, Ulrich, Teiber, John F., Horke, Sven
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335252/
https://ncbi.nlm.nih.gov/pubmed/22570791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/352857
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