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Ionizing Irradiation Protection and Mitigation of Murine Cells by Carbamazepine Is p53 and Autophagy Independent

BACKGROUND: Carbamazepine, a sodium channel blocker and pro-autophagy agent used in the treatment of epilepsy and trigeminal neuralgia, is also an ionizing radiation mitigator and protector. MATERIALS AND METHODS: We measured the effect of carbamazepine, compared to other pro-autophagy drugs (i.e. l...

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Detalhes bibliográficos
Main Authors: Kim, Hyun, Bernard, Mark E., Farkas, Amy, Goff, Julie, Kalash, Ronny, Houghton, Frank, Shields, Donna, Franicola, Darcy, Dixon, Tracy, Zhang, Xichen, Epperly, Michael, Wang, Hong, Cobanoglu, Murat Can, Greenberger, Joel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335174/
https://ncbi.nlm.nih.gov/pubmed/22523285
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