Diammonium Glycyrrhizinate Upregulates PGC-1α and Protects against Aβ(1–42)-Induced Neurotoxicity

Mitochondrial dysfunction is a hallmark of beta-amyloid (Aβ)-induced neurotoxicity in Alzheimer's disease (AD), and is considered an early event in AD pathology. Diammonium glycyrrhizinate (DG), the salt form of Glycyrrhizin, is known for its anti-inflammatory effects, resistance to biologic ox...

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Detalhes bibliográficos
Main Authors: Zhu, Xiaolei, Chen, Cong, Ye, Dan, Guan, Dening, Ye, Lan, Jin, Jiali, Zhao, Hui, Chen, Yanting, Wang, Zhongyuan, Wang, Xin, Xu, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335163/
https://ncbi.nlm.nih.gov/pubmed/22540007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035823
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