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A Proteomic View at T Cell Costimulation

The “two-signal paradigm” in T cell activation predicts that the cooperation of “signal 1,” provided by the T cell receptor (TCR) through engagement of major histocompatility complex (MHC)-presented peptide, with “signal 2″ provided by costimulatory molecules, the prototype of which is CD28, is requ...

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Detalhes bibliográficos
Main Authors: Lichtenfels, Rudolf, Rappl, Gunter, Hombach, Andreas A., Recktenwald, Christian V., Dressler, Sven P., Abken, Hinrich, Seliger, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335147/
https://ncbi.nlm.nih.gov/pubmed/22539942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032994
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