The Effect of Rosuvastatin in a Murine Model of Influenza A Infection

RATIONALE: HMG-CoA reductase inhibitors such as rosuvastatin may have immunomodulatory and anti-inflammatory effects that may reduce the severity of influenza A infection. We hypothesized that rosuvastatin would decrease viral replication, attenuate lung injury, and improve mortality following influ...

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Detalhes bibliográficos
Main Authors: Radigan, Kathryn A., Urich, Daniela, Misharin, Alexander V., Chiarella, Sergio E., Soberanes, Saul, Gonzalez, Angel, Perlman, Harris, Wunderink, Richard G., Budinger, G. R. Scott, Mutlu, Gökhan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335012/
https://ncbi.nlm.nih.gov/pubmed/22536437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035788
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