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Sprouty1 inhibits angiogenesis in association with up-regulation of p21 and p27
Sprouty1 (Spry1) is a conserved antagonist of FGF signaling. The goal of this study was to further explore the downstream mechanisms governing Spry1 inhibition of endothelial cell proliferation. Up-regulation of Spry1 in HUVECs inhibited tube formation on Matrigel (n = 6, P < 0.001). This was ass...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3334870/ https://ncbi.nlm.nih.gov/pubmed/20054616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-009-0359-z |
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