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Methylene blue plus light mediates 8-hydroxy 2'-deoxyguanosine formation in DNA preferentially over strand breakage.

Methylene blue (MB) plus light, in the presence of oxygen, mediates formation of 8-hydroxyguanine in DNA. The yield of 8-hydroxyguanine may be as much as from 2 to 4% of the guanines present. The results presented here show that treatment of supercoiled plasmid DNA with methylene blue plus light cau...

詳細記述

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書誌詳細
主要な著者: Schneider, J E, Price, S, Maidt, L, Gutteridge, J M, Floyd, R A
フォーマット: Artigo
言語:Inglês
出版事項: 1990
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC333472/
https://ncbi.nlm.nih.gov/pubmed/2155406
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