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CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome
Conformational change within the spliceosome is required between the first and second catalytic steps of pre-mRNA splicing. A prior genetic screen for suppressors of an intron mutant that stalls between the two steps yielded both prp8 and non-prp8 alleles that suppressed second-step splicing defects...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3334688/ https://ncbi.nlm.nih.gov/pubmed/22408182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.029421.111 |
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