Isoalantolactone Induces Reactive Oxygen Species Mediated Apoptosis in Pancreatic Carcinoma PANC-1 Cells

Isoalantolactone, a sesquiterpene lactone compound possesses antifungal, antibacteria, antihelminthic and antiproliferative activities. In the present study, we found that isoalantolactone inhibits growth and induces apoptosis in pancreatic cancer cells. Further mechanistic studies revealed that ind...

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Détails bibliographiques
Auteurs principaux: Khan, Muhammad, Ding, Chuan, Rasul, Azhar, Yi, Fei, Li, Ting, Gao, Hongwen, Gao, Rong, Zhong, Lili, Zhang, Kun, Fang, Xuedong, Ma, Tonghui
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2012
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334669/
https://ncbi.nlm.nih.gov/pubmed/22532787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.3753
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