Isoalantolactone Induces Reactive Oxygen Species Mediated Apoptosis in Pancreatic Carcinoma PANC-1 Cells

Isoalantolactone, a sesquiterpene lactone compound possesses antifungal, antibacteria, antihelminthic and antiproliferative activities. In the present study, we found that isoalantolactone inhibits growth and induces apoptosis in pancreatic cancer cells. Further mechanistic studies revealed that ind...

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Detalhes bibliográficos
Main Authors: Khan, Muhammad, Ding, Chuan, Rasul, Azhar, Yi, Fei, Li, Ting, Gao, Hongwen, Gao, Rong, Zhong, Lili, Zhang, Kun, Fang, Xuedong, Ma, Tonghui
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334669/
https://ncbi.nlm.nih.gov/pubmed/22532787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.3753
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