Decreased CXCR1 and CXCR2 expression on neutrophils in anti-neutrophil cytoplasmic autoantibody-associated vasculitides potentially increases neutrophil adhesion and impairs migration

INTRODUCTION: In anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides (AAV), persistent inflammation within the vessel wall suggests perturbed neutrophil trafficking leading to accumulation of activated neutrophils in the microvascular compartment. CXCR1 and CXCR2, being major che...

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Autors principals: Hu, Nan, Westra, Johanna, Rutgers, Abraham, Doornbos-Van der Meer, Berber, Huitema, Minke G, Stegeman, Coen A, Abdulahad, Wayel H, Satchell, Simon C, Mathieson, Peter W, Heeringa, Peter, M Kallenberg, Cees G
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334654/
https://ncbi.nlm.nih.gov/pubmed/22152684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3534
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