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Characterizing linkage disequilibrium and evaluating imputation power of human genomic insertion-deletion polymorphisms

BACKGROUND: Indels are an important cause of human variation and central to the study of human disease. The 1000 Genomes Project Low-Coverage Pilot identified over 1.3 million indels shorter than 50 bp, of which over 890 were identified as potentially disruptive variants. Yet, despite their ubiquity...

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Autori principali: Lu, James T, Wang, Yi, Gibbs, Richard A, Yu, Fuli
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334570/
https://ncbi.nlm.nih.gov/pubmed/22377349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-2-r15
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