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Genetic polymorphism of the iron-regulatory protein-1 and -2 genes in age-related macular degeneration

Iron can be involved in the pathogenesis of AMD through the oxidative stress because it may catalyze the Haber–Weiss and Fenton reactions converting hydrogen peroxide to free radicals, which can induce cellular damage. We hypothesized that genetic polymorphism in genes related to iron metabolism may...

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Hlavní autoři: Synowiec, Ewelina, Pogorzelska, Magdalena, Blasiak, Janusz, Szaflik, Jerzy, Szaflik, Jacek Pawel
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334491/
https://ncbi.nlm.nih.gov/pubmed/22331484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-012-1539-6
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