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Genetic polymorphism of the iron-regulatory protein-1 and -2 genes in age-related macular degeneration

Iron can be involved in the pathogenesis of AMD through the oxidative stress because it may catalyze the Haber–Weiss and Fenton reactions converting hydrogen peroxide to free radicals, which can induce cellular damage. We hypothesized that genetic polymorphism in genes related to iron metabolism may...

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Autors principals: Synowiec, Ewelina, Pogorzelska, Magdalena, Blasiak, Janusz, Szaflik, Jerzy, Szaflik, Jacek Pawel
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334491/
https://ncbi.nlm.nih.gov/pubmed/22331484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-012-1539-6
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