The residual repair capacity of xeroderma pigmentosum complementation group C fibroblasts is highly specific for transcriptionally active DNA.

We have measured removal of pyrimidine dimers in defined DNA sequences in confluent and actively growing normal human and xeroderma pigmentosum complementation group C (XP-C) fibroblasts exposed to 10 J/m2 UV-irradiation. In normal fibroblasts 45% and 90% of the dimers are removed from the transcrip...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Venema, J, van Hoffen, A, Natarajan, A T, van Zeeland, A A, Mullenders, L H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1990
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333446/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2308842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.3.443
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